Microneedling, originally known as collagen induction therapy or percutaneous collagen induction (PCI), is now a well-documented treatment option in atrophic acne scars and for skin rejuvenation. The therapeutic indications for this treatment option have increased over the last few years to include transdermal drug delivery, treatment of periorbital melanosis, actinic keratosis and varicella scars.
Microneedling relies on the principle of neocollagenesis and neovascularisation by fibroblast activation that occurs as a result of the release of growth factors following needle piercing of the stratum corneum. These growth factors are believed to be responsible for the beneficial effects of the procedure in the treatment of scars and photo ageing.
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